PRODUCTS
CT Lab HX Versatile X-ray Micro CT Scanner
High-performance benchtop
Rigaku CT Lab HX is a benchtop micro CT (computed tomography) scanner. The adjustable SOD (source-to-object distance) and SDD (source-to-detector distance) make this benchtop micro CT scanner flexible. It covers from 2.1-micron voxel resolution in the high-resolution mode and 200 mm FOV (field of view) in the large FOV mode. The CT Lab HX is equipped with a 130 kV – 39 W high-power X-ray source. The X-ray source settings and X-ray filters are adjustable to optimize the X-ray energy to various sample materials and sizes.
Rigaku CT Lab HX uses the cone-beam geometry. This geometry uses the X-ray beam divergence to magnify the sample image. The magnification factor is determined by the ratio of SOD (source-to-object distance) and SDD (source-to-detector distance). So to achieve high resolution, you can increase the SDD and/or decrease SOD. CT Lab HX has the flexibility to do them both in its compact design.
With the long SDD and short SOD settings, you can achieve 2.1-micron voxel resolution (~ 5-micron spatial resolution) on the CT Lab HX. This resolution can reveal micro cracks, voids, fibers in composites, etc.
WDXRF Spectrometers ZSX Primus IV
Elemental analysis of solids, liquids, powders, alloys and thin films
As a tube-above sequential wavelength dispersive X-ray fluorescence (WDXRF) spectrometer, the Rigaku ZSX Primus IV delivers rapid quantitative determination of major and minor atomic elements, from beryllium (Be) through uranium (U), in a wide variety of sample types — with minimal standards.
New ZSX Guidance expert system XRF software
ZSX Guidance supports you in all aspects of XRF measurement and data analysis. Can accurate analysis only be performed by experts ? No—that is in the past. ZSX Guidance software, with the built-in XRF expertise and know-how of skilled experts, takes care of sophisticated settings. Operators simply input basic information about samples, analysis components and standard composition. Measured lines with the least overlap, optimum backgrounds and correction parameters (including line overlaps) are automatically set with aid of qualitative spectra.
Exceptional light element XRF performance with inverted optics for superior reliability
ZSX Primus IV features an innovative optics-above configuration. Never again worry about a contaminated beam path or down time due to sample chamber maintenance. The optics-above geometry eliminates cleaning worries and increases up time. Providing superior performance with the flexibility for analyzing the most complex samples, the ZSX Primus IV WDXRF spectrometer features a 30 micron tube, the thinnest end-window tube available in the industry, for exceptional light element (low-Z) detection limits.
Accuva Cellect
Laser Capture Microdissection (LCM) System – Power and Precision in One System
For oncology, neuroscience, and other research areas that required cell enrichment, the Accuva Cellect sets you up for success in your downstream analysis. Isolating just the cells you want and capturing only the cells you want and enriching for specific cell types provides a more accurate genetic profile for earlier stage analysis.
Dual laser system
Enables a wide range of applications ranging from single-cell isolation to large biopsy extractions, expanding utility and helping to ensure reliability of cell capture across sample types without contamination or damage to morphology.
Allows rapid isolation of specific cells in five simple steps and quality control with visual inspection, making documentation and sample custody easy.
Flexible sample prep
Support for a wide range of slide types and sample preparation formats. If you have an existing workflow, we can work with that or we have validated workflow for you.
Compact design
The footprint is ~32% smaller microscope and laser systems, saving bench space.
PeproGMP Recombinant Proteins
Recombinant proteins are often among the key raw materials used in clinical manufacturing of biotherapeutics, so strong supply chain continuity and scaling capabilities are important considerations when choosing a GMP cytokine or other GMP protein supplier.
Thermo Fisher Scientific offers GMP proteins that can help you seamlessly scale your cell production process while meeting all clinical requirements. Gibco PeproGMP cytokines are designed and manufactured to support end-to-end manufacturing of cell therapies and other biotherapeutics.
All PeproTech GMP proteins are manufactured in E. coli using defined media, enzymes, and chemicals that are animal- and human-origin free. GMP recombinant proteins are available for a wide range of applications, including culture and modification of stem cells, immune cells, and organoids.
PeproTech GMP recombinant proteins are manufactured for use as ancillary materials by applying applicable principles of GMP and quality control requirements from USP (United States Pharmacopeia) Chapter <1043> Ancillary Materials for Cell, Gene, and Tissue-Engineered Products.
PeproGMP cytokines are developed and manufactured with quality, scale, and regulatory compliance in mind. Thermo Fisher Scientific has a dedicated 65,000 square foot facility for recombinant protein development and manufacture. All PeproTech recombinant proteins are now manufactured at this facility for high quality and consistency.
PeproTech proteins manufacturing facility features:
- Controlled and certified ISO Class 7 and Class 8 cleanrooms for GMP manufacturing
- Dedicated animal-free labs
- Centralized manufacturing to ensure lot-to-lot consistency
Download the PeproGMP brochure to view the full list of products.
PeproTech recombinant proteins
Recombinant cytokines, chemokines, and other RUO proteins
Most PeproTech recombinant proteins are based on native sequences from human, mouse, and rat, and are produced in bacterial, mammalian, or insect cells. Many PeproTech E. coli–produced proteins are animal origin–free as they are made without using animal-derived cell culture components or purification resins.
The PeproTech product line includes RUO recombinant cytokines important for research in:
- Stem cells
- 3D cell culture models
- Cancer cell biology
- Neurobiology
- Immunology
- Cardiovascular
PeproTech recombinant cytokines and proteins help life science, biotech, and pharma companies achieve success in their endeavors to discover new biological insights and develop cutting-edge cell and gene therapies.
Because every step of the production process is expertly managed within, PeproTech recombinant cytokines and growth factors are trusted for quality, consistency, and reliability as well as their ability to support the RUO-to-GMP transition.
Cell Lines & Primary Cells
We offer a variety of primary cultures and established cell lines, reagents, media, sera, and growth factors for your cell culture experiments.
Extracellular Matrices
To keep cells in a more native state in vitro, it helps to tailor their environment by including extracellular matrix (ECM) components that emulate what the cells experience in vivo. By including a relevant cell culture matrix, you can better recapitulate the in vivo environment in your cell culture model. Gibco extracellular matrices, scaffolds, and proteins provide in vivo-like morphology and physiologically relevant cellular environments for more realistic cell culture models.
- Geltrex products are reduced growth factor basement membrane extracts derived from mouse Engelbreth-Holm-Swarm (EHS) tumors.
- Laminin is the major glycoprotein in basement membranes. Mouse laminin facilitates the attachment and expansion of ESCs, iPSCs, and NSCs.
- Vitronectin (VTN-N) is a recombinant human protein that provides a defined surface for feeder-free culture of human pluripotent stem cells (PSCs). This cell culture matrix was designed for use with Essential 8 Medium and has been proven to maintain pluripotency and normal growth characteristics in multiple PSC lines.
- Collagen is the most widely used extracellular matrix protein for cell culture, facilitating cell attachment, growth, differentiation, migration, and tissue morphogenesis.
- Poly-D-lysine (PDL) is a synthetic ECM widely used to promote cell adhesion of a variety of cell types. PDL is also ideal for finicky cells, such as primary and PSC-derived neurons.
Below you will find overview of the cell lines, culture conditions, and analysis techniques being used in the transition from 2D to 3D cell models.
EVOS M3000 Imaging System
Compact, connected, and easily upgradable
The EVOS M3000 Imaging System is a fully integrated digital inverted benchtop microscope for two-color fluorescence, transmitted light, phase contrast, and color imaging. It is excellent for routine cell/tissue culture imaging applications. This system combines an easy user interface with powerful machine learning capabilities that allow users to quickly verify cell appearance, quality, and growth in seconds.
The EVOS M3000 offers you these important advantages:
- Easy installation—no maintenance, assembly, alignment, or calibration
- Automated real-time confluency analysis—includes pre-trained machine learning algorithm that can report cell confluency in the field of view at any time. As vessel is moved, confluency value automatically updates (in under a second on average).
- User-defined two-color fluorescence—with addition of EVOS light cubes, two fluorescence channels can be acquired
- Space-saving design—at 12 x 19 x 13 in. (W x D x H), system fits easily on lab bench or in cell culture hood
- Network-capable—can be connected to local wireless network for seamless data transfer to OneDrive™ or Thermo Fisher Connect accounts. Alternatively, system offers on-board storage or export to USB.
- Flexibility—choose from wide selection of EVOS-compatible objectives (1.25–60X) to best fit application and image quality needs.
Dynabeads Magnetic Beads
Dynabeads products center around the goals to provide reliable and reproducible results for the purification and analysis of cells, proteins, exosomes, DNA, RNA, and other molecules. Dynabeads magnetic beads and products deliver highly cited results in the research industry across multiple application areas. Meanwhile, Thermo Fisher Scientific provides exceptional service and support backed by over 30+ years of knowledge and expertise.
What are Dynabeads magnetic beads?
- Dynabeads magnetic beads are superparamagnetic particles—they exhibit magnetic properties when placed in a magnetic field but retain no residual magnetism once removed from the magnetic field
- Unique batch-to-batch reproducibility secures reproducible, quality results
- Spherical shape and defined surface chemistry minimizes chemical agglutination and non-specific binding
- Polymer shell on each bead protects your target from toxic exposure to iron
- Bioreactive molecules can be absorbed or coupled to their surface, and used to separate biological materials (cells, proteins, nucleic acids, etc.)
Dynabeads magnetic beads come in several sizes and different surface functionalities for use in a wide variety of applications. Some beads are precoupled with a biomolecule (ligand). The ligand can be an antibody, protein or antigen, DNA/RNA probe, or any other molecule with an affinity for the desired target.
Mr. Frosty™ Freezing Container
Freeze cells in tubes from 1 to 5 mL using the Thermo Scientific™ Mr. Frosty™ Freezing Container. The simple-to-use system is designed to achieve a rate of cooling very close to -1°C/minute, the optimal rate for cell preservation. It holds 12 to 18 tubes, and a screw top lid secures samples inside in the event of accidental container tipping.
Features:
- Holds 12 to 18 tubes and has profile height of 86 or 151mm (3-7/16 to 5-5/16 in.), which saves precious freezer space during the cooling process
- Screw top lid secures samples inside in the event of accidental container tipping
- Eliminates unreliable, improvised foam container devices
- Easy to use—requires only 100% isopropyl alcohol and a mechanical freezer
- No contact with the alcohol: no wicking, no label removal and no compromise of tube hand printing
Ordering Information:
Containers have 4.75 in. diameter (120mm) closure
Requires:
Isopropyl alcohol and a mechanical freezer
Gibco Cryopreservation Media
Freezing down cells guards against unplanned mutations, senescence, and contamination. While unprotected cell freezing is ordinarily lethal, cell freezing with cryopreservation media helps protect cells for long-term viability as well as minimizes freezing injury for an intact cell supply on your schedule.
View protocols for cell freezing and thawing for more information.
- Recovery Cell Culture Freezing Medium
A complete, ready-to-use freezing medium, the Recovery medium formulation avoids messy mixing. Using an optimized version of the classic DMEM, serum, and DMSO, Recovery cell freezing medium is ready to go when you are. When treated with Recovery medium, cells experience improved recovery and viability post-thaw.
- Synth-a-Freeze Cryopreservation Medium
Formulated without antibiotics, antimycotics, hormones, growth factors, serum or proteins, Synth-a-Freeze medium is defined and ready-to-use. Synth-a-Freeze medium is buffered with HEPES and sodium bicarbonate and designed for use with primary mammalian cell types including human keratinocytes, embryonic stem cells, neural stem cells, and mesenchymal stem cells.
- PSC Cryopreservation Kit
The PSC Cryopreservation Kit contains ready-to-use, xeno-free cryopreservation medium as well as a bottle of RevitaCell Supplement (100X). Together, these reagents minimize cell viability loss and unwanted cell differentiation while maximizing post-thaw recovery. Applications include pluripotent stem cells cultured in media systems, such as Essential 8 and StemPro hESC SFM, as well as other commercially available formulations. In addition, this kit can also be used to cryopreserve and recover peripheral blood mononuclear cells (PBMCs).
- RevitaCell supplement
Containing Rho-associated protein kinase (ROCK) inhibitors and antioxidant properties, the RevitaCell supplement typically recovers pluripotent stem cells at 40,000 viable cells/cm2, and significantly reduces the average post-thaw recovery time of most cryopreservation solutions. In addition to pluripotent stem cells, RevitaCell supplements can also be utilized with primary cells including neurons, human epidermal keratinocytes, and human corneal epithelial cells.
Cell Culture Imaging Dishes, Plates, Slides and Coverglass
The Thermo Scientific Nunc Cell Culture Imaging Products offer comprehensive solutions with flexibility and consistency to meet your needs in cell imaging applications, including fluorescence microscopy, phase contrast microscopy, confocal microscopy, live cell imaging, differential interference contrast (DIC) microscopy, and fluorescence in situ hybridization (FISH).
Featuring removable medium chambers, the Thermo Scientific Nunc Lab-Tek and Lab-Tek II Chamber Slide systems allow you to seed, incubate, fix, stain and image on a single microscope slide, saving time and labor in the immunohistochemistry work.
Thermo Scientific Nunc Lab-Tek and Lab-Tek II Chambered Coverglasses feature chambers mounted to coverslips to provide optimal characteristics required for high magnification, confocal, and live imaging analysis.
With minimum background noise, the Thermo Scientific Nunc 96- and 384-well Optical Bottom Plates offer a wide selection of colors and surfaces ideal for cell-based fluorescence and luminescence assays.
Thermo Scientific Nunc glass bottom dishes combine the convenience of standard 35 mm cell culture dishes with the optical characteristics of coverslips to solve commonly encountered issues during live-cell imaging, such as medium evaporation and contamination.
Thermo Scientific Nunc Flasks on Slides provide suitable solutions for cell karyotyping using single cell autoradiography or single-cell immunofluorescence.
