PRODUCTS
Navios EX
Powerful, Dependable Flow Cytometer
Strong and stable cytometer performance is fundamental when analyzing important clinical samples as every event matters. Designed specifically for the clinical laboratory the NAVIOS EX 10-color flow cytometer delivers proven reliability and stability performance with improved sample traceability and reporting functions.
This next generation cytometer leverages the advanced optics and laser technology of our award-winning CytoFLEX* research flow cytometer to provide clear, accurate population resolution for advanced cytometry applications, standardizes workflows for high throughput laboratories and delivers comparable results across multiple sites.
To ensure clinical labs have the confidence to meet today’s rigorous quality assurance obligations the Navios EX has two optional ready-to-use IVD reagent systems, the Navios Tetra System for simultaneous identification and enumeration of T, B and NK lymphocytes and the ClearLLab 10C System – the first FDA cleared and CE marked integrated leukemia and lymphoma immunophenotyping system.
- Laboratory Information System (LIS) bi-directional interface manages test orders, creates work lists automatically, minimizes manual data entry, tracks samples throughout the testing process, and eliminates transcription errors in the reporting process.
- The powerful lasers and integrated optics from the company’s CytoFLEX* instrument provide clear, accurate population resolution. With two different forward scatter angles, the Navios EX offers the flexibility of small particle detection as well as dim fluorescent population analysis.
- Automates the standardization workflow using target channels to enable consistent results over time as well as across sites using shared targets.
- Up to 12-parameters for identification of populations in complex advanced applications** with 10-color IVD capability to collect additional information from your user defined assays.
Clinical Antibodies
Beckman Coulter offers the largest portfolio of CE-IVD and ASR conjugated antibodies validated against clinical standards. Antibodies are developed and manufactured according to current Good Manufacturing Practices (cGMP), the highest quality standards in the industry, ensuring optimal antibody panel performance.
Largest portfolio of conjugated antibodies validated against the clinical standards CE-IVD and ASR.
Beckman Coulter’s tandem dyes stability and lot-to-lot consistency ensure reproducible and reliable results.
Broad portfolio of clones and dyes allows for flexible panel design.
Contact our team of experts – Flow cytometry application specialist – for guidance.
Research Antibodies
Flow cytometry antibodies, assays and reagents
Explore our diverse collection of antibodies, assays, beads and buffers support leading research areas.
Invitrogen™ eBioscience™ flow cytometry antibodies and Invitrogen™ flow cytometry assays and reagents.
Find tools, protocols and more detailed information or gain a basic understanding of techniques to help you plan and execute your experiments.
- Flow Cytometry Antibody Selection Tool
- Flow Cytometry Panel Builder
- Flow Cytometry Protocols
- Invitrogen eBioscience Resources
- Fluorophore and reagent selection guide for flow cytometry
Vi-CELL BLU Cell Viability Analyzer
The faster Vi-CELL BLU cell analyzers automates the Trypan Blue Dye Exclusion method for cell viability analysis. The Vi-CELL BLU expedites processing by now having the option to use a 24-position sample carousel or a 96 well plate for sample delivery. Additional enhancements incorporated in the Vi-CELL BLU include:
– Fully automated sample preparation, analysis and post-run cleaning
– Small sample size
– Fast sample processing time
– Log-in samples on the fly
– Single sign-on with Active Directory
– Small laboratory footprint
– Flexible sample introduction – carousel or 96 well plate
– User-friendly reagent system
– Cell viability reported in percentage, concentration, and cell count
– Large sample capacity
– Data integrity tools for 21 CFR Part 11 compliance”
Multisizer 4e Coulter Counter
The Multisizer 4e particle sizer and counter is the most accurate and flexible particle characterization device available, boasting an unparalleled sizing range of 0.2 – 1600 μm. The new 10 μm Aperture allows users to study sub-cellular and micro-particles as small as 200 nm, while the advanced noise reduction system for small apertures improves measurement accuracy. Generated data are processed using patented digital pulse processing technology and can be saved and later re-analyzed. This technology provides ultra high resolution and accuracy unattainable through any other technologies: detection of 1 particle in 1 ml of a sample with the optimal instrument configuration. Analysis results are not dependent on particle shape, structure, or optical properties. t uses the Coulter principle to detect particles via electrical zone sensing, regardless of the particle’s nature or optical properties. This makes it an ideal tool for detecting and counting a wide variety of particles such as: Mammalian cells, Bacteria, Yeast, Abrasives, Toner particles, Spheroids, Cells and Large protein aggregates etc.
LS 13 320 XR Particle Size Analyzer
The LS 13 320 XR offers best-in-class particle size distribution data from advanced PIDS ( (Polarization
Intensity Differential Scattering) technology, which enables high-resolution measurements and an expanded dynamic range. Like the LS 13 320, the XR particle size analyzer provides fast, accurate results, and helps you streamline workflows to optimize efficiency. Some big improvements help you reliably spot small differences that can have a huge impact on your particle analysis data. Direct measurement range from 10 nm – 3,500 µm Automatically highlights pass/fail results for faster quality control Enhanced software that simplifies method creation for standardized measurements New control standards to adequately verify instrument/module performance.
HIAC 9703+ Pharmaceutical Liquid Particle Counter
HIAC 9703+ liquid sampler and PharmSpec Software for Parenteral Drug Final Product Testing to USP<787>, <788> & EP2.9.19 :
PharmSpec Software works with the HIAC 9703+ liquid particle counter system to test parenteral products for sub-visible particle content using light obscuration in accordance with USP<787>, <788> and EP 2.9.19.
Flexible calibration at multiple flow rates improves ease of sampling for varying sample viscosities and volumes.
Ease of use and data integrity are prioritized in PharmSpec with features such as login credentials controlled by Microsoft Active Directory, multi-level user rights, automated pass/fail compendial reporting, comprehensive audit trail, and auto-flush routines for improved walkaway operation. In addition to the built-in compendial test routines, user-defined SOPs can be programmed into the counter using PharmSpec Software’s Procedure Builder.
MET ONE HHPC+ Handheld Air Particle Counters
MET ONE HHPC+ Series handheld particle counters allow easy ISO Class 5 to 7 monitoring in hard-to-reach places. Lightweight with a high-resolution display, these handheld counters are ideal for routine monitoring of controlled environments and mini-environments, easy filter leak troubleshooting for particle-contamination issues, spot-checking critical areas, and targeting particle generation within process equipment.
ISO 14644-1 industry standard
CFR 21 Part 11 compliance enabled
0.3 μm – 10.0 μm particle detection
2-6 channel detection
Single-hand operation
PC access to particle counting data via Ethernet, USB, or cable for data transfer options
MET ONE 3400+ Series GMP Cleanroom Routine Environmental Air Particle Counter
MET ONE 3400+ Series Portable Airborne Particle Counter allows users to load their routine environmental monitoring SOP sampling map and sampling configuration for each location directly into the counter, so that the SOP becomes an interactive sampling map directly on the counter screen to guide users doing daily sampling. This helps reduce training requirements and sampling data errors/omissions.
MET ONE 6000 / 7000 Remote Air Particle Counter
MET ONE 6000 air particle counters are a compact design with flexible sizing, flow rate and communication options that address the specific needs of cleanroom environments within the pharmaceutical, semiconductor, hard disk drive and flat panel display industries providing ISO 21501 accuracy for continuous particle monitoring. Reduce initial installation cost with MET ONE 6000 remote air particle counter’s integrated multi-parameter measurements.
The MET ONE 7000 provide high accuracy non-viable particle monitoring for cGMP/FDA compliance. Stainless steel wash-down resistant enclosure and VHP tolerant optics protect the instrument while ISO 21501 certified calibration assures accurate continuous monitoring in aseptic and sterile pharmaceutical production environments.
Facility Monitoring Systems (FMS)
Scalable Facility Monitoring Systems (FMS) that can be configured to meet a wide spectrum of cleanroom management needs for various industries—including pharmaceutical production. Among parameters that can be efficiently and reliably monitored using a Beckman Coulter FMS are non-viable/viable air sampling, differential pressure, air temperature and relative humidity. All of the company’s FMS solutions are based on an open-architecture platform designed to enable easy, streamlined integration with existing customer systems (SCADA). Each instrument is built around proven MET ONE technology, including the portable MET ONE 3400 series for routine monitoring and cleanroom classification, as well as the 6000 and 7000 series of fixed, non-viable air particle counters. MET ONE software platforms feature intuitive interfaces to help make them easy to use, thereby reducing the potential for human error that can occur with manual SOP monitoring. To avoid losses from product contamination, stack lights, audible alarms and process shutdown signals from a Beckman Coulter FMS can prompt an immediate production line response whenever an excursion happens. In addition, to help centralize reporting and simplify EUGMP/FDA compliance (e.g., for ISO 14644 and 21 CFR Part 11), Beckman FMS data can be integrated into a single-release, electronically signed paperless report.
Frequency Modulation Spectroscopy (FMS) Headspace analyzers
• FMS-Oxygen Headspace Analyzer
• FMS-CO2 Headspace Analyzer
• FMS-Pressure/Moisture Headspace Analyzer
• FMS-Water Activity Headspace Analyzer
Frequency Modulation Spectroscopy (FMS) is utilized by LIGHTHOUSE laboratory instruments to determine the amount of gases within the headspace of pharmaceutical containers. Using laser absorption, light from a near-infrared laser is tuned to match an internal absorption frequency of various molecules and passed through a glass sample container in the headspace above the product. The amount of laser light absorbed is proportional to the concentration of the specified gas in the headspace. The rapid and non-destructive nature of the analysis allows for multiple measurements on the same sample over time, which yields more accurate results. Additionally, this prevents waste, which saves costs on both waste disposal items and valuable product. The benchtop FMS Analyzers are straightforward to use, meaning operators do not require special expertise to use these robust, portable devices, and accuracy does not depend on operator skill. The benchtop headspace gas analyzers can be used throughout the entire product lifecycle, from development to QC laboratory applications to at-line, in-process control of headspace gas / water levels in production.
