Transfection Reagents

We offer transfection reagents for DNA, siRNA, RNA, and protein delivery, providing a range of options to suit your transfection experiment:
• DNA delivery—Transient and stable transfection of DNA plasmids. DNA transfection is used to study gene function and regulation, mutational analysis and biochemical characterization of gene products, effects of gene expression on the health and life cycle of cells, as well as for large scale production of proteins for purification and downstream applications.
• RNA delivery—Transient transfection of mRNA or RNAi molecules. mRNA transfection, which allows the production of recombinant proteins without the need for nuclear entry, is useful for short-term studies of gene expression and has emerged as a promising application for vaccine studies. RNAi molecules facilitate gene knockdown, which can be used in analyses of protein function and phenotype, function recovery, pathway analysis, in vivo knockdown, and drug target discovery.
• Protein delivery—CRISPR-Cas9 transfection allows for genome editing in broad applications such as stem cell engineering, gene therapy, tissue and animal disease models, and engineering disease-resistant transgenic plants.
Invitrogen Lipofectamine reagents have become the most referenced transfection reagents with over 50,000 citations. You continue to choose these reagents due to their wide acceptance as the best and most reliable available. Lipofectamine reagents offer you the ability to consistently transfect many cell types with high efficiency and exceptional ease of use.
Click “Learn more” for interactive transfection selection tool to find products, citations, and protocols optimized for your transfection experiments. Input information on your experiment type, cell line, and payload to unlock solutions.