GeneArt Gene and Protein Synthesis Services

Your gene, your way—complete experimental workflow solutions from gene synthesis to protein expression and purification.
Combining the convenience of our online ordering system and Invitrogen GeneOptimizer technology, cutting-edge Invitrogen GeneArt services are here to help meet your gene synthesis needs for increased protein expression via optimized synthetic genes or directed evolution services to rationalize protein engineering.
The GeneArt GeneOptimizer algorithm goes beyond basic codon optimization to help improve transcription, mRNA stability, and translation for better protein yields.

Click “Learn more” and explore the GeneArt Services selection guide

Description

Invitrogen GeneArt services selection guide

For all service options, no physical template is required, and you can take advantage of our industry-leading sequence optimization for improved expression and sequence design flexibility.

GeneArt Strings DNA Fragments GeneArt Cloned Gene Synthesis GeneArt Gene-to-Protein
What we do Synthesis of linear dsDNA fragments up to 3 kb Synthesis of DNA of interest, cloned into standard vector or expression vector of choice (ready to use) Expression and purification of proteins from mammalian cells, starting from only the electronic sequence
Advantages
  • Synthesis of large sequences
  • Synthesis of complex sequences (e.g., high/low GC content)
  • Downstream services available
  • All production steps from a single-source provider
  • Experienced scientists
  • Reliable and advanced expression systems (ExpiCHO and Expi293 Expression Systems)
  • Expression scales from 30 mL to 25 L
Hands-on time Medium Low None
Deliverables 200 ng linear dsDNA pool, dried 5 µg plasmid DNA clone, dried Protein of interest and expression vector used for transfection
Production time
  • 3–5 business days for <2 kb
  • 6–8 business days for 2–3 kb
  • 7 business days for genes <1,200 bp
  • 9 business days for genes <3,000 bp
  • Acceleration options available
Typically 30 business days
Length Up to 3 kb Up to 100 kb N/A
Quality control Bulk sequencing 100% sequence-verified Detailed documentation, including Coomassie-stained PAGE gel and western blot

 

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