PRODUCTS
Bioreactor Systems by Thermo Fisher Scientific
Discover the advantages of a comprehensive bioreactor portfolio, enabling scalability from research to cGMP manufacturing
Biopharmaceutical applications requires a solution to support robust cell growth. Thermo Scientific offers a range of bioreactors perfectly suited for mammalian cell culture and microbial fermentation applications that span process development, clinical trials, and large-scale commercial biomanufacturing. The bioreactor portfolio offers options from 1 L glass bioreactors to 2,000 L single-use bioreactors. Our system solutions allow you to choose the ideal match for your process parameters. Bioreactor Systems:
Glass Bioreactors
Open Architecture Single-Use Bioreactors
Rocker Bioreactor
DynaDrive Single-Use Bioreactor
Bioreactors systems by Infors
Bench-top and pilot bioreactors offer practical solutions for mammalian cells, bacteria and yeast cultivations. The bench-top bioreactor offers features beyond those of other devices of its class.
Bench-Top Bioreactors
Minifors 2
A compact and easy-to-use bioreactor with a full range of application possibilities. It is a complete package that enables both, beginners and experienced users to easily perform applications.
Multifors 2
With Multifors 2 you can work with up to six bioprocesses in parallel. Thanks to a selection of preconfigured packages and a variety of connection possibilities and options, you will be ideally equipped for optimizing sophisticated bioprocesses on a small scale.
Labfors 5
The Labfors 5 is suitable for microorganisms, phototrophic organisms as well as solid subtrates and enzymatic bioprocesses. There are almost no limits to its uses.
Pilot Bioreactors
Techfors-S
The Techfors-S contains exactly the same components as Infors bench bioreactors. This ranges from the pumps via the gassing line to the touch screen controller and the associated software. Both beginners as well as process experts will be able to manage easily. Minimum working volume of 3 liters. The double jacket of the Techfors-S vessels guarantees optimum temperature control even at low starting volumes – essential for modern fed-batch fermentations. Thanks to its compact design and mobile stand, the Techfors-S can be used anywhere.
Techfors
There are practically no limits on flexibility with regard to design and operation, since each pilot bioreactor model is built individually according to your needs. You specify the requirements – we implement them after performing a thorough feasibility study.
Cell culture media
Since 1962, GIBCO have been empowering progress in bioprocessing around the world. Our pioneering end-to-end products, process development and customization services can help maximize productivity while reducing costs and time to market. Our portfolio include:
• Culture solution for Biosimilars, Vaccine production ,Cell and Gene therapy.
• High-performing CHO media designed to optimize your workflow, including media that is chemically defined, animal origin–free, serum-free, and more.
• Manufacture customized media or your formulation for production, provide non-GMP media prototyping, and create custom packaging, supporting your entire media manufacturing journey.
• Range of feeds and supplements that can enhance your cell culture up to a 2- to 5-fold increase over batch culture.
Gibco Peptones
Enhance your cell culture performance
We offer an extensive portfolio of nutritionally diverse animal origin (AO) and animal origin—free (AOF) peptones to supplement a variety of cell culture media.
Alternative to serum – Offers essential nutrients shown to increase performance and production in a variety of vaccine applications.
Protective effects – Fortifies cell culture medium to improve cultivation, productivity, and anti-apoptosis properties during scale-up.
Performance enhancer – Reduces time to market with high-performance products that meet stringent quality standards and rigorous raw sourcing policies.
XCell® ATF System
Simplify and intensify upstream bioprocessing. The XCell® ATF System, in single-use or stainless steel format, delivers superior cell retention. High impact upstream applications include N-1 perfusion, high productivity harvest, long-term perfusion and seed train intensification. XCell® ATF Systems simplify and fast-track upstream intensification by providing an integrated solution consisting of an XCell® ATF Device, XCell® ATF Controller, software, tubing, pressure sensors and accessories. The family of Systems supports diverse applications across development from 1L to 5000 L.
KrosFlo® KR2i TFF System
Single-use fully integrated benchtop TFF system for use in lab scale process development ranging from 2mL – 15L. Compatible with hollow fiber or flat sheet filters, this system offers many user-defined set-point controls so you can run complex applications in fully-automated modes. The fully integrated KrosFlo KR2i TFF System features a digital peristaltic pump, graphical LCD display, digital pressure monitor, KR2i Pump head, automatic backpressure valve, filter module stand, and KF Comm real-time data collection software. Highly configurable and versatile, the KrosFlo KR2i utilizes a number user-defined set-points to run complex application processes with numerous built-in safety alarms and stops. The system can run up to two stackable pump heads for higher flow rates.
Spectrum® Hollow Fiber Modules
Spectrum® Hollow Fiber Filter Modules: Ideal for ultrafiltration, diafiltration and microfiltration, single-use hollow fiber filters for tangential flow filtration are packed in housings engineered to handle high pressures, with a choice of fiber chemistries and sizes from process development to manufacturing. Spectrum® Hollow Fiber Membranes: Fully encapsulated in single-use modules, the membranes used in the hollow fiber filter modules from Repligen are constructed using four chemistries that are anisotropic in structure to deliver high flux rates, excellent separation, and low protein binding for higher product yields.
Bioprocess Resins
When you need high performance and high throughput on a large scale, POROS bulk chromatography resins enable outstanding performance for process-scale bioseparations. Utilized in multiple processes, these breakthrough resins combine optimal particle size and pore structure with a rigid backbone and proprietary chemistries. POROS 50 µm resins demonstrate exceptionally high resolution, dynamic binding capacity, and capture efficiency over a range of flow rates and are primarily used in polish applications.
CaptureSelect affinity resins offer excellent selectivity resulting in higher yields and improved purity in the initial capture step. We have developed numerous products for large-scale purification of various biologics such as antibodies and antibody fragments, fusion proteins, hormones, and viruses.
TOYOPEARL and TSKgel Process Media (TOSOH)
TOSOH BIOSCIENCE: TSKgel and TOYOPEARL resins are specifically designed for use in biopharmaceutical production. Based on a rigid polymer structure, they show excellent physical strength and flow characteristics, resulting in faster process throughput. Optimized pore diameters and narrow particle size distribution allow rapid kinetics and exceptional resolution.
TOYOPEARL and TSKgel resins are applied from capture, through intermediate purification, to polishing. Target molecules range from peptides and proteins to oligonucleotides and plasmids.
QuantStudio 1 Real-Time PCR System
The QuantStudio 1 Real-Time PCR System is a basic instrument for new and experienced users looking for a quality product at an affordable price. With a large interactive touchscreen and pre-optimized protocol templates, set up is easy.
Run reactions of up to 100 μL and detect differences as small as 1.5-fold in singleplex reactions, with results in approximately 40 minutes. The QuantStudio 1 system is also equipped with Connect, Thermo Fisher Scientific’s cloud-based platform, allowing you to remotely monitor your runs in real time, analyze sophisticated data sets in minutes, securely store data, and share results online with colleagues across institutions and around the world.
QuantStudio 3 and 5 Real-Time PCR Systems
QuantStudio 3 and 5 real-tme PCR systems are factory-calibrated for quick installation and immediate use. These systems detect differences in target quantity as low as 1.5-fold, allow remote monitoring, and feature optional cloud-based Applied Biosystems analysis modules and data sharing.
Designed for both new and experienced users, they support 96-well (0.2ml or 0.1ml) or 384-well (QS5 only) consumables. The systems also feature multiplexing capabilities for up to 6 targets and software to enable 21 CFR Part 11 compliance.
QuantStudio 6 and 7 Pro Real-Time PCR Systems
The Applied Biosystems QuantStudio 6 and 7 Pro real-time PCR systems deliver greater flexibility to support a variety of applications and throughput requirements. The systems’ smart features are designed to reduce contamination by allowing you to set up your run hands-free. Schedule and monitor your run from your mobile device, set-up your experiment, analyze data, and share your results from your computer no matter where it is or where you are.
The QuantStudio 6 and 7 Pro systems’ 96-well blocks incorporate VeriFlex technology for precise temperature control. These blocks are divided into isolated zones that allow separate cycling conditions within the same run, perfect for optimization. You can also increase your throughput with interchangeable blocks that accommodate 96-well 0.2 ml blocks, 96-well 0.1 ml blocks, 384-well blocks and TaqMan Array Cards (QuantStudio 7 Pro model only). Other unique features of the QuantStudio 7 Pro system include automation compatibility and software features to assist with 21 CFR Part 11 compliance.
