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SECOM
The SECOM platform is a fluorescence microscope made to be integrated with a scanning electron microscope. It enables you to do correlative microscopy extremely fast, with the highest optical quality and overlay accuracy. Thanks to its integrated design, switching from fluorescence to electron imaging is seamless and instantaneous. And with the automated alignment procedure, you are directly imaging the right location at a high resolution. Imaging with the SECOM is just like using a fully equipped high-end optical wide-field microscope, without compromise on either optical or electron performance. The system is installed as a retrofit by replacing the door to the vacuum chamber and can be fitted to most scanning electron microscopes. Using the SECOM for thin sections allows you to use fluorescent markers for pinpointing regions of interest, locating rare events, screening large areas and identifying subcellular structures on a molecular basis. By using multicolor labelling you can have the enormous toolbox of fluorescent markers available in nanometer resolution electron images.