OptiXTRACT Sample Recovery Aid

The OptiXTRACT Sample Recovery Aid is a controlled, standardized extraction instrument designed to streamline the post-density gradient ultracentrifugation (DGUC) recovery phase. The system standardizes the manual extraction of separated biological fractions, allowing operators to isolate up to 5 distinct bands per tube. By containing the tube within a stable, mechanical mount, the platform removes direct manual handling during extraction to secure sample layers and minimize physical turbulence. Engineered with a compact footprint, the device fits directly inside standard biosafety cabinets to maintain strict sterility and environmental containment protocols.

Core Technologies & Operational Features

• Guide-Rail Controlled Piercing: Utilizes a rigid slide rail system that guides needle movements along a fixed vector, facilitating hands-free puncturing and mitigating accidental needle sticks or sharps hazards.

• Secure Tube Holders: Features heavy-duty, stable positioning mounts that lock various centrifuge tubes firmly in place, eliminating tube slippage, preventing spills, and minimizing fluid agitation.

• Dimmable LED Illumination: Equipped with an integrated, adjustable LED back-light system that illuminates the sample tube directly, allowing operators to clearly visualize and target fraction bands without lifting or shifting the tube.

• Precision Graduations: Incorporates clear, highly visible measurement markings along the assembly to facilitate repeatable, accurate needle positioning across identical runs.

• Sterility Optimization: Designed to support a sterile workflow, featuring a single-use sterile syringe adapter mechanism optimized for cleanroom and biosafety cabinet integration.

Primary Preparative Applications

• Precision Viral Band Recovery: Standardized needle positioning for harvesting high-purity fractions of Adeno-Associated Virus (AAV), Lentivirus, and Adenovirus directly from gradient matrices.

• Exosome Fraction Extraction: Controlled collection of distinct extracellular vesicle (EV) and exosome subpopulations without disturbing adjacent, non-target density layers.

• Iso-Density Gradient Harvesting: Mechanical recovery of target biological materials from density media arrays, including continuous or step gradients composed of Cesium Chloride (CsCl), Sucrose, or Iodixanol.

• Subcellular Organelle Isolation: Clean extraction of isolated cellular components, such as intact mitochondria, nuclei, or microsomal layers, following differential centrifugation.

Looking for the complete solution? Discover how OptiMATE, Optima XPN, and OptiXTRACT integrate seamlessly into an end-to-end separation workflow. Visit our Knowledge Center Hub.