Thermo Scientific™ S4 Series Centrifuges

Models included: S4T (Ventilated Benchtop) | S4TR (Refrigerated Benchtop) | S4FR (Refrigerated Floor-Standing)

The Thermo Scientific S4 Series centrifuges provide high-capacity, heavy-duty sample separation for high-throughput clinical diagnostic laboratories, cell culture facilities, and bioprocessing centers. Supporting swing-out capacities up to 4 x 1,000 mL (4 Liters) and speeds up to 25,830 x g, the S4 Series combines quiet operation with eco-friendly GreenCool refrigeration technology. Manufactured in a certified zero-waste facility in Germany, it delivers sustainable, high-capacity productivity while ensuring rigorous sample protection and temperature stability.

Technological Innovations & Core Capabilities

• Auto-Lock™ Rotor Exchange: Fast, push-button, tool-free rotor installation supporting up to 13 application-specific rotors for seamless workflow transitions.
• GreenCool™ Natural Refrigerant: Advanced R290 cooling system featuring a Global Warming Potential (GWP) of just 3, zero ozone depletion, and reduced energy consumption (S4TR / S4FR).
• High-Capacity Ergonomics: Accommodates up to 4 Liters of sample volume in both space-saving benchtop and floor-standing (S4FR) footprints designed to optimize bench space.
• ClickSeal™ Biocontainment Lids: Certified glove-friendly, one-handed aerosol-tight sealing system for hazardous biological samples and clinical materials.
• Dual Regulatory Certifications: Available in IVD-MD (EU IVDR Class A / FDA Listed Class 1) for regulated diagnostic centers and General Use configurations for research.

Intended Applications

• Clinical Diagnostics: High-volume processing of primary blood collection tubes and diagnostic samples under IVD compliance.
• Cell Culture & Bioprocessing: Large-volume harvesting, cell pelleting, and media separation in 15 mL, 50 mL, and 250 mL/500 mL/1,000 mL vessels.
• Genomics & Proteomics: High-speed separation for spin-column purification, multi-well microplates, and high-density cell lysates.