CryoArc™ Pico -190°C LN2-Based Automated Storage System

The CryoArc™ Pico Automated LN2-Based Storage System is engineered for automated cryogenic preservation of high-value biological samples from discovery phases through clinical applications. Designed to fit spaces with a standard 8-foot ceiling height and 32-inch doorways, the system delivers sample security and inventory management within a minimized physical footprint.

The system utilizes liquid nitrogen vapor phase technology to maintain a consistent and uniform -190°C storage temperature for stored samples from top to bottom. By utilizing automated storage and retrieval workflows, it allows users to access needed samples without exposing non-targeted materials to uncontrolled transient warming events or exposing staff to cryogenic dangers. This ensures precise process control and thermal stability during retrieval, keeping samples safely below the water glass transition temperature (Tg -135°C).

Key Advantages

• Thermal Exposure Mitigation: Automated sample access prevents innocent samples from undergoing transient warming events.

• Footprint Optimization: Maximizes internal labware density while passing through standard facility clearance pathways.

• Rigorous Integrity Control: Enhances sample protection and absolute traceability compared to manual cryogenic dewar freezers.

Ideal Applications

• Research laboratories and university biobanks

• Clinical cell banks and medical centers

• Cell & Gene Therapy (CGT) workflows and organoid research

Robotic Automation & Labware Handling

• Insulated Robotic Tower: Accommodates sample boxes from 1 to 7 inches tall or cryogenic cassettes. Laboratory units placed into the system are automatically delivered to user-specified or software-optimized storage positions.

• Granular Inventory Tracking: System inventory tracking is fully operational at the tube, cassette, and microplate level to ensure uncompromised chain-of-custody documentation.

Integrated Software & Regulatory Compliance

• Integrated CryoArc Software Platform: Tracks individual sample location, sample movement parameters, and user access metrics across the sample’s operational lifetime.

• Real-Time Telemetry Logging: Captures critical environmental data, including internal temperature uniformity, unexpected system events, operational alarms, liquid nitrogen levels, and nominal LN2 usage rates.

• Enterprise LIMS Connectivity: Employs an optional WebAPI module to seamlessly integrate tracking telemetry with homegrown or enterprise Laboratory Information Management Systems (LIMS).

• Audit Trail Generation: Fully supports adherence to FDA 21 CFR Part 11 compliance standards. All sample history, user validation logs, and performance parameters can be downloaded in a standardized format for immediate inclusion in official audit reports.

Infrastructure Redundancy & Disaster Protection

• Extended Hold Time Stability: Provides up to 10 days of continuous static temperature stability to protect stored biological assets during total facility electrical outages or liquid nitrogen supply interruptions.

• Onboard Integrated UPS: Features an onboard uninterruptible power supply (UPS) to sustain the software storage environment, internal telemetry data collection, and system monitoring parameters during sudden power disruptions.

Technical Specifications

Storage Capacity (Vials): Stores up to 17,248 x 1.0ml Azenta cryotubes OR 8,800 x 2.0ml Azenta cryotubes

Storage Capacity (Boxes/Cassettes): Accommodates (88) 2” Cryoboxes (or equivalent) OR 400 x 25ml cassettes

Operating Temperature Baseline: -190°C (Liquid Nitrogen Vapor Phase environment)

Emergency Static Holding Time: 10 days to maintain a baseline of -135°C

System Physical Dimensions (H x W x D): 95.5″ x 42.7″ x 56.8″ (2,426 mm x 1,085 mm x 1,443 mm)

System Structural Weight: 1,122 lbs (511 kg) Empty / 1,402 lbs (640 kg) Full Estimated Baseline

Maximum Structural Floor Load: 84 lbs/ft² (410 kg/m²)

Electrical Input Parameters: 110V / 220V, Single Phase

System Power Consumption Metrics: 100 Watts (Idle) / 220 Watts (Maximum output)

LN2 Supply Line Interface: 1/2″ NPT Male Fitting to existing LN2 Supply Line

LN2 Operational Supply Pressure: 22-35 psig (1.52 – 2.41 bar) under open valve workflow

LN2 Evaporation Rate (Nominal): Approximately 9 Liters per day

Operating Environment Limits: Temperature: 18°C – 27°C (65°F – 80°F) | Humidity: Maximum 50% rH (non-condensing)

Regulatory & Compliance Index: CE Mark Directives, China RoHS, Conflict Materials, EU REACH, EU RoHS